Optimal screening for genetic diseases

نویسندگان

چکیده

برای دانلود باید عضویت طلایی داشته باشید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Optimal screening for genetic diseases.

Screening for genetic diseases is performed in many regions and/or ethnic groups where there is a high prevalence of possibly malign genes. The propagation of such genes can be considered a dynamic externality. Given that many of these diseases are untreatable and give rise to truly tragic outcomes, they are a source of societal concern, and the screening process should perhaps be regulated. Th...

متن کامل

Optimal mix of screening and contact tracing for endemic diseases.

Two common means of controlling infectious diseases are screening and contact tracing. Which should be used, and when? We consider the problem of determining the cheapest mix of screening and contact tracing necessary to achieve a desired endemic prevalence of a disease or to identify a specified number of cases. We perform a partial equilibrium analysis of small-scale interventions, assuming t...

متن کامل

Optimal Trend Tests for Genetic Association Studies of Heterogeneous Diseases

The Cochran-Armitage trend test is a standard procedure in genetic association studies. It is a directed test with high power to detect genetic effects that follow the gene-dosage model. In this paper, the author proposes optimal trend tests for genetic association studies of heterogeneous diseases. Monte-Carlo simulations show that the power gain of the optimal trend tests over the conventiona...

متن کامل

Optimal Path Diagnosis by Genetic Algorithm for NoCs

Nowadays Network-on-Chips is used instead of System-on-Chips for better performance. This paper presents a new algorithm to find a shorter path, and shows that genetic algorithm is a potential technique for solving routing problem for mesh topology in on-chip-network.

متن کامل

A Method for Solving Optimal Control Problems Using Genetic Programming

This paper deals with a novel method for solving optimal control problems based on genetic programming. This approach produces some trial solutions and seeks the best of them. If the solution cannot be expressed in a closed analytical form then our method produces an approximation with a controlled level of accuracy. Using numerical examples, we will demonstrate how to use the results.

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

ژورنال

عنوان ژورنال: Economics & Human Biology

سال: 2014

ISSN: 1570-677X

DOI: 10.1016/j.ehb.2014.08.002